Basketball spoof “Semi-Pro” starring Will Ferrell marks the final standalone New Line released from Bob Shaye and Michael Lynne’s. The comedy is a sure winning of this box office weekend even though it has an R rating.

The other big openers are targeted for the female crowd. “The Other Boleyn Girl,” period film starring Natalie Portman and Scarlett Johansson as sisters hostile toward each other for the love of King Henry VIII.

The modern-day fairy tale “Penelope,” starring Christina Ricci, Reese Witherspoon and James McAvoy, which has been promoted extensively at Screenhead is the other big opener. The film is about a young heiress who is born with a pig nose. I am voting for “Penelope” to have the number one spot this weekend.