Actress Vera Farmiga will be in the skies with George Clooney in Jason Reitman’s Up in the Air.

According to Variety, the tale focuses on a human resources executive whose sole joy in life occurs from the prospect of notching his millionth frequent-flyer mile, a goal he engages in with zeal while the rest of his life falls apart because he is continuously on the road.

Farmiga is set to play a businesswoman who develops a romantic relationship with Clooney’s character through meetings in airports and hotels around the country.

Filming begins in late February in St. Louis, Miami and Las Vegas.